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Granulated copper oxide nanocatalyst: A mild and efficient reusable catalyst for the one-pot synthesis of 4-amino-5-pyrimidinecarbonitriles under aqueous conditions

Ahmadi, S. J ; Sharif University of Technology | 2011

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  1. Type of Document: Article
  2. DOI: 10.1007/s00706-011-0579-2
  3. Publisher: 2011
  4. Abstract:
  5. An efficient method for the synthesis of 4-amino-5-pyrimidinecarbonitriles by the three-component reaction of malononitrile, aldehydes, and N-unsubstituted amidines under aqueous conditions using CuO microspheres as catalyst is reported. The catalyst exhibited remarkable reusable activity. Graphical abstract: [Figure not available: see fulltext.]
  6. Keywords:
  7. 4-Amino-5- pyrimidinecarbonitriles ; Aldehydes ; Amidines ; CuO microspheres ; Malononitrile
  8. Source: Monatshefte fur Chemie ; Volume 142, Issue 11 , November , 2011 , Pages 1163-1168 ; 00269247 (ISSN)
  9. URL: http://link.springer.com/article/10.1007%2Fs00706-011-0579-2