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Study of Antibacterial Performance of Metal Oxide Nanostructures and their Effect on Bacterial Growth Kinetics

Afkhami, Fatemeh Sadat | 2020

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 52856 (04)
  4. University: Sharif University of Technology
  5. Department: Physics
  6. Advisor(s): Naseri, Naimeh; Zaker Moshfegh, Alireza
  7. Abstract:
  8. Fighting contagious microbial diseases is considered a serious health issue, which has attracted much attention in worldwide. Thus, development of new materials based on nanostructures as a new generation of antibiotics to address this challenge has been of interest to researchers in recent years. Nanostructures based on metallic oxide semiconductors such as oxides with light absorption, production of electron-hole pairs in needle like structures cause tearing bacterial membrane and eventually destroy the bacterium. To this end, we designed experiments to study mechanism and physics governing the process of bacterial degradation to determine the best conditions for inhibiting bacteria growth. Two experimental methods were used to study this performance. In the first method, the nanostructure was exposed to a suspension of the bacterium and in the second method it was exposed to a drop of bacteria. The reason for changing the method of testing in more details is discussed in this dissertation. The results of the second method show that zinc oxide nanowires have 99.20%, branched zinc oxide nanowires have 99.40%, Nitrogen-doped Graphene Quantum dots have 30.64%, branched zinc oxide nanowires decorated with nitrogen-doped graphene quantum dots, with a concentration of 20µL have 96.30%, with a concentration of 50µL have 92.53% and with a concentration of 100µL have 93.59%, antibacterial properties in the light with Broadband 400-500 nm. The cause of the counter-expected branched zinc oxide nanowires decorated with nitrogen-doped graphene quantum dots can be attributed to the saturation effect of these materials, which is discussed in detail in this paper
  9. Keywords:
  10. Antibacterial Activity ; Graphene Quantum Dots (GQDs) ; Antibacterial Resistance ; Epidemic ; Zinc Oxide Nanostructures ; Growth Kinetics

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