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The influence of temperature alterations on eccentric contraction-induced isometric force and desmin loss in ratmedial gastrocnemius muscle

Vasaghi Gharamaleki, B ; Sharif University of Technology | 2008

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  1. Type of Document: Article
  2. DOI: 10.3923/jms.2008.162.169
  3. Publisher: 2008
  4. Abstract:
  5. In this study isolated perfused rat muscle was used to examine the direct effect of temperature changes on the eccentric contraction-induced force and desmin loss. The left medial gastrocnemius muscle was separated and the entire lower limb was transferred into a prewarmed (35°C) organ bath. Temperature was adjusted to 31 or 39°C before and during eccentric contractions. Maximal isometric force and desmin loss were measured after 15 isometric or eccentric contractions. According to our data, organ bath temperature changes before or during eccentric contractions had no significant effect on force loss. However, a strong correlation between desmin loss and temperature changes before (r = 0.93, p<0.05) and during (r = 0.87, p<0.05) eccentric contractions was observed. Present results suggest that cooling before or during eccentric contractions may decrease desmin loss
  6. Keywords:
  7. Desmin ; Oxidoreductase ; Triphenyltetrazolium ; Animal tissue ; Controlled study ; Cooling ; Correlation analysis ; Eccentric muscle contraction ; Electrostimulation ; Enzyme activity ; Gastrocnemius muscle ; Immunohistochemistry ; Male ; Muscle force ; Muscle isometric contraction ; Muscle perfusion ; Muscle resection ; Nonhuman ; Protein depletion ; Rat ; Temperature
  8. Source: Journal of Medical Sciences ; Volume 8, Issue 2 , 2008 , Pages 162-169 ; 16824474 (ISSN)
  9. URL: https://scialert.net/abstract/?doi=jms.2008.162.169