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2-D Modeling of Blood Flow in Mitral Valve During its Closing and Opening

Jamshidi, Hadi | 2014

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  1. Type of Document: M.Sc. Thesis
  2. Language: English
  3. Document No: 55047 (58)
  4. University: Sharif University of Technology, International Campus, Kish Island
  5. Department: Science and Engineering
  6. Advisor(s): Firoozabadi, Bahar; Saeedi, Mohammad Saeed
  7. Abstract:
  8. Problems with the mitral valve can make the heart less efficient at pumping blood around the body. Severe problems can lead to heart failure if the valve is not surgically repaired or replaced. A simple approximation of the heart geometry is used and the valve dimensions are based on reported measurements. The primary objective for this study is to design and simulate the opening and closing behavior of the mitral valve using 2D fluid-structure interaction (FSI) model using ADINA software in order to evaluate and investigate the hemodynamic performance and problems of mitral valve, in which the blood is described as a viscous incompressible fluid, and the mitral valve is described as an elastic solid structure. An initial validation of the model is provided by comparing the velocity profile to clinical measurements from magnetic resonance imaging (MRI). The results obtained suggest that differences in the young’s modulus of the leaflets play an important role in the magnitude of the displacement of the mitral valve. In addition, by increasing the value of the young’s modulus, the values of the E/A ratio and the vortex formation time during diastolic are increased, and the flow rate is decreased. In conclusions, this model will be used in future, to determine stresses of the mitral valves and to investigate the heart valve failure.
  9. Keywords:
  10. Fluid-Structure Interaction ; Hemodynamics ; Systolic Blood Pressure ; Diastolic Blood Pressure ; Mitral Valve Hemodynamic Performance ; Heart Diseases

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