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- Type of Document: M.Sc. Thesis
- Language: Farsi
- Document No: 45138 (06)
- University: Sharif University of Technology
- Department: Chemical and Petroleum Engineering
- Advisor(s): Abdekhodaie, Mohammad Jafar; Bastani, Daruosh
- Abstract:
- Transport phenomena i.e. momentum, heat and mass transfer are occurring inside the eye constantly. Any disturbance in each of these could lead to diseases or ocular problems. Konwledge of transport phenomena can help surgeons and specialists to identify problems more easily and cure the problems effectively. Further more, these phenomena have a great impact on drug delivery inside the eye. Therefore deep understanding of them makes investigation of different therapies easy and convenient. Consequently this understanding could lead to choose the best method and route of administration available. A precise model which is in consistence with the real human eye has been developed and the ocular transport phenomena have been investigated. First the heat and mass transfer inside the normal human eye is studied, then, the effects of presence of vitreous substitutes on the transport phenomena is analyzed. Finally the mass transfer inside the eye is modeled by the data available for the intravenous injection. The present model can simulate the transport phenomena in different conditions and also different therapies like intracameral or intravitreal injection in whole the eye
- Keywords:
- Drug Delivery ; Mass Transfer ; Heat Transfer ; Momentum Transfer ; Mathematical Modeling
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