Loading...

Conjugated Linoleic Acid (CLA) Production Via Chemical Method Using Vegetable Oils

Afarin, Maryam | 2016

637 Viewed
  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 48592 (06)
  4. University: Sharif University of Technology
  5. Department: Chemical and Petroleum Engineering
  6. Advisor(s): Alemzadeh, Iran
  7. Abstract:
  8. Conjugated linoleic acid (CLA), a mixture of positional and geometrical isomers of linoleic acid with conjugated double bonds, has gained considerable attention because of its anticarcinogenic and obesity treatment properties. The most biologically active CLA isomers are 9c, 11t-18:2 and 10t, 12c-18:2. Natural sources of CLA are fat of meat and dairy products derived from ruminant animals. About 3 grams of CLA per day is necessary to provide human health needs, but each person receives about 10% of this value from natural resources, thus production of CLA as a dietary supplement is necessary. CLA is produced from biological and chemical methods but because of high yield of chemical production it is preferred, and from the chemical production methods alkali isomerization of safflower oil due to its high efficiency, minimal production of undesired isomers and production of both essential isomers was used in this study. The aim of this study was to optimize the production of CLA in alkali isomerization of safflower oil using response surface methodology (RSM) and the effect of three reaction variables contains temperature, reaction time and amount of KOH on CLA production investigated using design-expert software. The optimal condition determined as follow temperature 187.6 c˚ , reaction time 2.12 hr and the amount of KOH 48.7 gr at this point 72% total CLA was produced also enrichment of10t, 12c-18:2 was done by urea fractionation and effects of content of CLA and ratio of urea to CLA was evaluated in efficiency of enrichment. Purification up to 86% CLA was the best result
  9. Keywords:
  10. Conjugated Linoleic Acid (CLA) ; Purification ; Chemical Processes ; Safflower Oil ; Unea Fractionation

 Digital Object List

 Bookmark

No TOC