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The possibilities of palladium-catalyzed aromatic cyanation in aqueous media
Vafaeezadeh, M ; Sharif University of Technology
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- Type of Document: Article
- DOI: 10.1016/j.inoche.2016.08.014
- Publisher: Elsevier
- Abstract:
- Owing to the inherent incompatibility with water, cyanation of aryl halides may be the most challenging category of palladium-catalyzed coupling reactions. The major challenges are attributed to the catalyst deactivation by the soluble cyanide (CN−) ions and desirable conversions only could be obtained by employing toxic organic solvents. The current minireview highlights mechanistic insights and breakthrough achievements for this reaction in the aqueous media
- Keywords:
- Coupling reactions ; Cyanation ; Green synthesis ; Palladium ; Water
- Source: Inorganic Chemistry Communications ; Volume 72 , 2016 , Pages 86-90 ; 13877003 (ISSN)
- URL: http://www.sciencedirect.com/science/article/pii/S1387700316302702