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Analysis of Appearance of Bone Barrier in HIFU Treatment Method

Torkinejad Ziarati, Pouriya | 2018

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  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 50492 (08)
  4. University: Sharif University of Technology
  5. Department: Mechanical Engineering
  6. Advisor(s): Ahmadian, Mohammad Taghi; Firoozbakhsh, Keykhosrow
  7. Abstract:
  8. Currently, the HIFU (High Intensity Focused Ultrasound) therapy method is known as one of the most advanced surgical techniques in tumor ablation therapy. Simulation of the HIFU therapy in the case of appearance of bon barrier is essential in HIFU planning to improve the usefulness and efficiency of treatment in brain tumor cases. In this work, linear, thermoviscous equations are applied for simulation of phase correction array and steering method, after analysis of performance, these methods are used in a 3D human brain and skull model to estimate thermal ablation in case of using these methods. Results indicate that the maximum focal pressure of 1.42 and 1.65 MPa can be achieved for transducer power of 40 and 46 W. Simultaneous solving of the acoustic pressure equation and Pennes’s bio-heat equation are used to determine the temperature rise at focal point and the ablated area. The simulated results provide information about the behavior of the focalized ultrasound in interaction with brain tissue. The performance of phased array HIFU transducer can be improved for treatment considering the lesion size, temperature rise in tissue and choosing best range of operational power
  9. Keywords:
  10. Ultrasonic Waves ; High Intensity Focused Ultrasound (HIFU)Method ; Cancer Treatment ; Acoustic Cavitation ; Brain Tumor

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