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Facile and efficient one-pot protocol for the synthesis of benzoxazole and benzothiazole derivatives using molecular iodine as catalyst

Matloubi Moghaddam, F ; Sharif University of Technology | 2006

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  1. Type of Document: Article
  2. DOI: 10.1080/00397910600781448
  3. Publisher: 2006
  4. Abstract:
  5. Rapid and efficient condensation reactions of 2-aminothiophenol and 2-aminophenol with various aldehydes were carried out using I2 in solvent-free conditions with or without microwave irradiation to afford the corresponding 2-substituted benzothiazole and benzoxazole derivatives in good to excellent yields. Copyright © Taylor & Francis Group, LLC
  6. Keywords:
  7. 2 aminophenol ; Aldehyde ; Benzothiazole derivative ; Benzoxazole derivative ; Iodine ; Catalysis ; Chemical reaction ; Drug structure ; Drug synthesis ; Melting point ; Microwave irradiation ; Nuclear magnetic resonance ; Polymerization ; Thin layer chromatography
  8. Source: Synthetic Communications ; Volume 36, Issue 17 , 2006 , Pages 2543-2548 ; 00397911 (ISSN)
  9. URL: https://www.tandfonline.com/doi/abs/10.1080/00397910600781448