Loading...

Investigation of the Influence of Nanoparticle & Nanofluidic Conduit Geometry on Ionic Transport

Bakouei, Mostafa | 2021

517 Viewed
  1. Type of Document: M.Sc. Thesis
  2. Language: Farsi
  3. Document No: 53680 (08)
  4. University: Sharif University of Technology
  5. Department: Mechanical Engineering
  6. Advisor(s): Taghipoor, Mojtaba
  7. Abstract:
  8. Resistive pulse sensing (RPS) has proved to be a viable method for detection and characterization of micro and nano particles. This method works based on ionic current variation inside nanopores. Modern fabrication methods have introduced different nanopore geometries for resistive pulse sensors therefore studing the effects of geometry on sensing performance of nanaopores is important. Numerical simulation has been used to study a wide variation of nanopore’s geometry configurations and study the physics behind this phenomena. Based on the results, numerical simulation could be used as a fast and easy tool for size determination for nanopore. To compare the sensing performance of different nanaopore platforms, four resistive pulse quality parameters were investigated – sensitivity, pulse duration, pulse amplitude and resolution. The results revealed that large cone angle and low aspect ratio nanopores have higher resolution and sensitivity, but their low duration could be a challenge in the process of detecting the resistive pulse. In this thesis the effets of surface charge density of nanopore and nanoparticle on ionic current and resistive pulse amplitude has been studied. The results show that the translocation of highly charged nanoparticles through nanopores make conductive pulse instead of resistive pulse. The findings of the present work can be used in practical applications where choosing the optimal pore geometry is of crucial significance
  9. Keywords:
  10. Nano-Biosensor ; Numerical Simulation ; Nanopore ; Nanofluid ; Ion Transport ; Resistive Pulse Sensing

 Digital Object List

 Bookmark

No TOC