Sharif Digital Repository

A novel Fe3O4/poly (aniline-naphthylamine) (ANI-NA)-based nanocomposite was synthesized by chemical oxidative polymerization process as a magnetic sorbent for magnetic solid phase extraction. The extraction efficiency of this sorbent was examined by isolation of rhodamine B (RhB), a mutagenic and carcinogenic dye from aquatic media in dispersion mode. The efficiency of the synthesized Fe3O4/copolymer composite was examined and compared with Fe3O4/polyaniline (PANI) and Fe3O4/polynaphthylamine (PNA) by quantification of RhB using spectrofluorimetry. Among them, Fe3O4/poly (ANI-NA) nanocomposite showed a prominent efficiency. The scaning electron microscopy (SEM) image of the synthesized... 

Cancer treatment is one of the most challenging issues of recent years. Extensive researches have been conducted in various fields of medicine, pharmacy, and medical physics in this regard. Today, considering nanotechnology developments, researchers believe that full cancer treatment is possible through the use of nano-systems designed with scientific background to overcome the defects of previous methods. In this research, the main purpose is to design and synthesize multifunctional hybrid nanostructures with favorable optical and magnetic properties providing a way to combine chemotherapy and thermal treatment. Accordingly, two different structures were designed and experimentally... 

The main methods have been used clinically for cancer treatment are included: surgery, chemotherapy, radiation therapy and hyperthermia. Hyperthermia (heat therapy) treatment method in which by raising the temperature of the tumor it removed. Magnetic hyperthermia is known as a kind of hyperthermia that have been represent appropriate results. In this study, using iron oxide nanoparticle coated with graphene for cancer treatment under a magnetic field of the laser. In the first stage, graphene oxide nanosheets and nanoparticles Magntayt are synthesized by chemical oxidation and co-precipitation, respectively. At the end, the nanoparticles on the substrate of graphene layer is obtained... 

Long-term deactivation of a commercial K-promoted Fe2O3 catalyst used in the dehydrogenation of ethylbenzene to styrene monomer was studied using thirty months of operating data of three industrial SM radial fixed bed adiabatic reactors. The Langmuir-Hinshelwood, Hougen-Watson model (LHHW) was used for reaction kinetics modeling. The kinetics of coking from ethylbenzene and styrene and the short-term deactivation function due to the quick coke formation were also considered in the model. The kinetics of long-term deactivation of the catalyst for ethylbenzene dehydrogenation to styrene between 550 and 630 °C were determined by allowing the effects of temperature and time on the catalyst... 

In this thesis, heterogenous catalysts based on magnetic nanoparticles were synthesized. In these catalysts, magnetic nanoparticles were coated with defferent fuctional groups to produce a catalyst with magnetic properties which is easily separated from the reaction medium. The structure of synthesized catalyst was characterized using techniques such as transmission electron microscopy (TEM), scanning electron microscope (SEM), Fourier transform infrared spectroscopy (FTIR), and CHNS elemental analysis. Easy preparation, low cost, biodegradability and high thermal stability are advantages of these catalysts. At the end, the catalytic properties of resulted catalysts were investigated in many... 

A novel thermo responsive decorated system is designed by coating Fe3O4 magnetic nanoparticles with conjugated Pluronic-ATPEG copolymer incorporated into the PEG-PMDA Hydrogel for drug delivery to the cartilage tissue. Grafted copolymer was synthesized by reaction between carboxylated Pluronic and amino terminated Poly ethylene glycol (ATPEG) and confirmed by FTIR and NMR analysis. The magnetic nanoparticles were modified with the produced copolymer and characterized by TEM, HRTEM, XRD, DLS, and VSM. A typical product has 13 nm magnetic core and 105 nm hydrodynamic diameter with narrow size distribution. DLS results showed that there was an increase in size by increasing temperature from 25℃... 

The use of magnetic nanoparticles modified with proper surface agent and the ability of controlling by magnetic field, that can induce colloidal stability, is considered as a vector to transfer DNA plasmid, or pDNA in short, in the field of gene therapy. In thiss research, pH-responsive dextran-based magnetic nanogels (dextMNGs) were synthesized via inverse mini-emulsion method. Fourier transformation infrared spectroscopy (FTIR) showed that magnetite nanoparticles (MNPs) were successfully modified with arginine and had amine terminals. FTIR, also, proved that aldehyded dextran was crosslinked by arginine modified magnetite nanoparticles (RMNPs) via pH sensitive imine bonds. X-ray... 

The use of magnetic compounds for drug delivery and magnetic imaging has been studied in many studies. The easy use of magnetic particles makes them widespread. By applying a magnetic field, the particles reach the desired position and return to the original state by cutting off the field. The use of these magnetic materials in the nanoscale also adds other benefits, including: convenient and rapid transfer of nanoparticles, rapid repulsion of the kidneys, reducing the risk of overdose, etc. In recent years, the use of quantum dots for the diagnosis and treatment of tumors has attracted much attention. The use of hybrid quantum dots and magnetic nanoparticles can incorporate the desired... 

Cancer is one of the most important problems that affects public health. If this disease is diagnosed quickly in the patient's body, it can be prevented and treated by determining the stage of the disease and establishing a treatment protocol. Magnetic resonance imaging (MRI) and fluorescence imaging (FI) are among the imaging methods. In order to increase the contrast of images, researchers have turned to the synthesis of materials under contrast agents, which improve diagnostic sensitivity. Synthesis of nanoparticles as multi-mode contrast agents can enhance imaging methods. In this research, the synthesis and characterization of the multifunctional Fe3O4-Mn3O4-LCysteine@g-C3N4 QDs system... 

Transition metal oxides and carbon based materials (especially graphene) are common electrode materials in supercapacitors. The metal oxide limitation is due to their high agglomeration and low electrical conductivity. On the other hand graphene base materials due to their unique structure as well as high electrical conductivity and high surface area increase energy storage capability. However, chemically produced graphene generally suffers from high agglomeration and re-stacking after removal from the solution and drying, g, which results in reduced electrochemical performance of graphene sheets in supercapacitors. To take full advantage of these two groups of materials, it is expected that... 

Photocatalysts are compounds that can perform oxidation and reductions in the presence of light. One of the most known applications for photocatalyst is degrading organic contaminants in wastewater and making them harmless to the environment.In this project, a magnetic photocatalyst based on Fe3O4@ZnO/N-RGO has been synthesized and characterized with FT-IR, FE-SEM and EDS, XRD, and TGA. Moreover, photocatalytic dye degradation reactions for Rhodamine B, Methylene Blue, and Methyl Orange have been investigated and compared in the presence of Fe3O4@ZnO/N-RGO, Fe3O4@ZnO/RGO, Fe3O4@ZnO, and ZnO. Furthermore, the performance of the photocatalyst has been studied for 5 consecutive reactions and... 

As contrast enhancement agent, two different structures of superparamagnetic nanoparticles were synthesized. Iron oxide nanoparticles were prepared through an alkaline coprecipitation method of Iron (II) and (III) ions. PEG-6000 was used as biocapping material and its effect on particle size, colloidal stability and cytotoxicity was evaluated. On the other hand, novel core/shell structures were produced by NaBH4 reduction process of iron (III) in an aqueous media following by further oxidation by two different methods using (CH3)3NO oxygen transferring agent and exposure to oxygen flow. In both cases, structural examinations were conducted via X-ray diffraction, electron microscopy and... 

Present study is designed to determine the effect of manganese content in primitive inverse spinel structure of iron oxide nanoparticles. PEG coated water base ferrofluids of Mnx¬Fe3-xO4 (0<0>1)nanoparticles were prepared by co-precipitation method in presence of nitrogen gas and ultrasonic waves using NaOH as a base for biomedical purposes. The crystallite size and structure of synthesized nanoparticles were studied using atomic absorption spectroscopy (AAS), X-ray diffraction spectrometry (XRD), field emission scanning electron microscopy (FE-SEM) and dynamic light scattering (DLS) methods. Thermogravimetric analysis (TGA) and Fourier transform infrared spectroscopy (FTIR) were used to... 

Age-related macular degeneration (AMD) is the most common cause of vision loss in those aged over 50. There are two main types of AMD, Wet and Dry form. Wet AMD is more severe though more treatable. There are three conventional treatments for AMD including laser therapy, surgery and intravitreal injection of anti-VEGF into the eye. Delivery of drugs to the posterior segment of the eye is still challenging and several implants and devices are currently under investigation for their ability to stimulate the retina, producing visual percepts. The application of intravitreal bevacizumab (Avastin) has expanded tremendously from the time of its introduction into ophthalmic care since 3 years ago.... 

Age-related macular degeneration (AMD) is the most common cause of vision loss in those aged over 50. There are two main types of AMD, Wet and Dry form. Wet AMD is more severe though more treatable. There are three conventional treatments for AMD including laser therapy, surgery and intravitreal injection of anti-VEGF into the eye. Delivery of drugs to the posterior segment of the eye is still challenging and several implants and devices are currently under investigation for their ability to stimulate the retina, producing visual percepts. The application of intravitreal bevacizumab (Avastin) has expanded tremendously from the time of its introduction into ophthalmic care since 3 years ago.... 

One of the major problems in cancer treatment is side effects of treatments. Today, scientists have developed smart nanocarrier for diagnosis and drug delivery that can circulate in the bloodstream, pass the body's immune system to kill cancer cells and attach to the cancer cells to deliver drugs, without the side effects that are in other treatments, such as chemotherapy. magnetic nanoparticles coated by biodegradable polymers are one of the smart polymers. In this study, iron oxide nanoparticles with amine group on their surface are coated by starch modified by methyl acrylate then reacted with hydrazine and hydrazide functional group is formed that can chemically be bonded with the... 

Iron oxide nanoparticles were synthesized using microemulsion technique as MRI contrast agents. Utilization of nanoparticles for biological applications and in this case as MRI contrast agents needs particles to be of small size and also narrow size distribution. For this aim, the effect of several parameters on size and size distribution has been studied. These parameters include water/surfactant ratio, precursor’s concentration and amount of polymer employed to improve nanoparticles colloidal stability. XRD, FE-SEM and TEM results reveal that the synthesized nanoparticles had small size (about 10 nm iron oxide core and 20 nm overall diameter) and possessed narrow size distribution (15-21... 

Superparamagnetic iron oxide nanoparticles (SPION) with proper surface coatings are increasingly being evaluated for clinical applications such as hyperthermia, drug delivery, magnetic resonance imaging, transfection, and cell/protein separation. Since the particles with various sizes exhibit different flow rates in the same environment (same capillary size), it is essential to use particles of a desirable size for targeted drug delivery and imaging. Particles of different sizes may be exposed to different viscosities and behave differently, particularly with regard to their velocities as they move through capillaries. In the present work, SPION with different size, purity, shape and... 

Water-gas shift reaction (CO(g) + H2O(g) ↔ CO2(g) + H2(g)) is performed as the key step in the hydrogen and ammonia industrial plant. In this work, Fe/Cr/Cu high temperature water gas shift catalysts were synthesized by coprecipitation method, using sulfate precursors, in order to improve the catalytic performance and particular emphasis is placed on the catalytic activity affected by aging time, precipitating agent and ways of increasing the mechanical strength. Finally the prepared and industrial catalysts were compared when they were situated in the operating conditions (at 360oC and 2 bar) and were characterized by BET, XRD, TPR, TEM and crushing strength analysis. Catalysts being made...