Sharif Digital Repository

Whole-body vibration (WBV) has been identified as one of the serious risk factors leading to spinal disorders, particularly in professional drivers. Although the influential factors in this area have been investigated epidemiologically, finite element (FE) modeling can efficiently help us better understand the problem. In this study, a modified HYBRID III dummy FE model which was enhanced by detailed viscoelastic discs in the lumbar region was utilized to simulate the effect of WBV on lumbar spine loads. Spinal responses to the vertical sinusoidal vibrations of a generic seat were obtained and spinal injury risk factors were calculated. Effects of variation of excitation frequencies, three... 

Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of soft materials is done using light tweezers. This work investigates micrometer particle movements in the optical trap and also, when they are connected to a red blood cell. The tweezers allow the Newtonian fluid viscosity, such as water and glycerin, to measure the mechanical properties of viscoelastic... 

Efforts have been made to study the behavior of complex materials in micrometer dimensions with various techniques. One of these methods is the use of optical tweezers for biophysical applications. Red blood cells, as the most abundant blood-forming cells, play an important role in the life of living organisms, and their unique mechanical properties are important. In this report, the study of soft materials is done using light tweezers. This work investigates micrometer particle movements in the optical trap and also, when they are connected to a red blood cell. The tweezers allow the Newtonian fluid viscosity, such as water and glycerin, to measure the mechanical properties of viscoelastic... 

Poly(vinyl alcohol) (PVA) is a biocompatible polymer which can be physically crosslinked by Borax to form hydrogel. PVA-Borax (PB) hydrogel is a promising candidate for drug delivery system. Therefore, it is necessary to find the quantitative relationship between drug release rate and network structure of PB hydrogels to predict and control drug release rate. In this work, at first step the optimum ratio of Borax: PVA was determined by studying the interactions between PVA chains and Borax molecules by means of Fourier transform infrared spectroscopy, while viscoelastic properties of prepared PB hydrogels were measured in the oscillatory shear flow field. In the following, curcumin as a... 

Poly (vinyl alcohol) and nano-diamond, PVA/ND, hydrogels were prepared and assessed as prosthetic material suitable for replacement of the nucleus pulposus. The hydrogels were prepared by gamma irradiation at various doses (15 kGy, 25 kGy, 35 kGy, 45 kGy) and at various ND concentrations ranging from 0.25 wt.% to 3 wt.%. Extent of gelation, equilibrium water content, and viscoelastic properties of swelled hydrogels at definite water contents were measured and examined as a function of ND concentration as well as gamma dose. According to viscoelastic measurements, the strength of hydrogels increased considerably over that of pure PVA at a low concentration of ND. By increasing irradiation... 

The dummies currently used for predicting vehicle occupant response during frontal crashes or whole-body vibration provide insufficient information about spinal loads. Although they aptly approximate upper-body rotations in different loading scenarios, they overlook spinal loads, which are crucial to injury assessment. This paper aims to develop a modified dummy finite element (FE) model with a detailed viscoelastic lumbar spine. This model has been developed and validated against in-vitro and in-silico data under different loading conditions, and its predicted ranges of motion (RoM) and intradiscal pressure (IDP) maintain close correspondence with the in-vitro data. The dominant frequency... 

In the present study, dynamic stability of a viscoelastic cantilevered pipe conveying fluid which fluctuates harmonically about a mean flow velocity is considered; while the fluid flow is exhausted through an inclined end nozzle. The Euler-Bernoulli beam theory is used to model the pipe and fluid flow effects are modelled as a distributed load along the pipe which contains the inertia, Coriolis, centrifugal and induced pulsating fluid flow forces. Moreover, the end nozzle is modelled as a follower force which couples bending vibrations with torsional ones. The extended Hamilton's principle and the Galerkin method are used to derive the bending-torsional equations of motion. The coupled... 

A direct numerical simulation approach is utilized to understand the oscillatory shear rheology of a confined suspension of magnetic chains formed by paramagnetic circular cylinders under the influence of an external magnetic field. The common assumption of gap-spanning chains made in the literature is relaxed in this work, so that a fully suspended (periodic) array of magnetic chains is formed. In this sense, the effective rheological parameters are only influenced through a layer of fluid adjacent to the walls. All tests are conducted at very low but finite particle Reynolds numbers, and typical inertial effects are discussed. The main aim of the present study is to investigate the... 

Optical tweezers are proven indispensable single-cell micro-manipulation and mechanical phenotyping tools. In this study, we have used optical tweezers for measuring the viscoelastic properties of human red blood cells (RBCs). Comparison of the viscoelastic features of the healthy fresh and atorvastatin treated cells revealed that the drug softens the cells. Using a simple modeling approach, we proposed a molecular model that explains the drug-induced softening of the RBC membrane. Our results suggest that direct interactions between the drug and cytoskeletal components underlie the drug-induced softening of the cells. © 2018 Optical Society of America  

In this paper, the dynamics of a viscoelastic plate resting on a viscoelastic Winkler foundation and traversed by a moving mass is studied. The Laplace transform is employed to derive the governing equation of the problem. Thereafter, an analytical-numerical method is proposed in order to determine the dynamic response of the plate. The method is based on transforming the governing partial differential equation into a new solvable system of linear ordinary differential equations. To that extent, the proposed solution proves to be applicable to plates made of any viscoelastic material and with various boundary conditions. Moreover, the moving mass may travel at any arbitrary trajectory with... 

This paper presents an analysis of the combined electro-osmotic and pressure-driven axial flows of viscoelastic fluids in a rectangular microchannel with arbitrary aspect ratios. The rheological behavior of the fluid is described by the complete form of Phan-Thien–Tanner (PTT) model with the Gordon–Schowalter convected derivative which covers the upper convected Maxwell, Johnson–Segalman and FENE-P models. Our numerical simulation is based on the computation of 2D Poisson–Boltzmann, Cauchy momentum and PTT constitutive equations. The solution of these governing nonlinear coupled set of equations is obtained by using the second-order central finite difference method in a non-uniform grid... 

The biofluids being manipulated in lab-on-a-chip devices usually contain elastic macromolecules. Accordingly, for an accurate modeling of the relevant flow physics one should invoke viscoelastic constitutive equations. In this paper, attention is paid toward the hydrodynamic dispersion by the fully developed electroosmotic flow of PTT viscoelastic fluids in slit microchannels of low zeta potential. Adopting the Taylor–Aris approach, analytical solutions are derived for late-time solute concentration and effective dispersion coefficient. Finite element-based numerical simulations are also conducted to monitor the broadening of an analyte band from the moment of injection. Both approaches are... 

Self-healing materials, as a class of intelligent materials, are capable to recover a part of the weakened mechanical properties induced by damage. In this article, based on the thermodynamics of irreversible processes, employing the effective configuration in the continuum damage-healing mechanics, a viscoelastic–viscoplastic constitutive model is presented. In the constitutive model development, we adopt an additive decomposition of the total strain into elastic, viscoelastic, and viscoplastic parts. In this regard, defining the damage and healing variables and employing the strain energy equivalence hypothesis, stress and strain tensors in the effective configuration are obtained.... 

Actin is known as the most abundant essentially protein in eukaryotic cells. Actin plays a crucial role in many cellular processes involving mechanical forces such as cell motility, adhesion, muscle contraction, and intracellular transport. However, little is known about the mechanical properties of this protein when subjected to mechanical forces in cellular processes. In this article, a series of large-scale molecular dynamics simulations are carried out to elucidate nanomechanical behavior such as elastic and viscoelastic properties of a single actin filament. Here, we used two individual methods namely, all-atoms and coarse-grained molecular dynamics, to evaluate elastic properties of a... 

One of the most important problems facing structural engineers is the analysis of dynamic behavior of bridges subjected to moving vehicles. In addition, viscoelastic supports under bridges change their dynamic behavior under passing traffic loads. This paper presents how to model a bridge with viscoelastic supports and how the maximum dynamic stress of bridges changes during the passing of moving vehicles. Furthermore, this paper presents an algorithm to solve the governing equation of the bridge with viscoelastic supports as well as the equation of motion of a real European truck with different speeds, simultaneously. Using viscoelastic supports with appropriate characteristics can make a... 

Asphalt binder is responsible for the thermo-viscoelastic mechanical behavior of asphalt concrete. Upon application of pure compressive stress to an asphalt concrete specimen, the stress is transferred by mechanisms such as aggregate interlock and the adhesion/cohesion properties of asphalt mastic. In the pure tensile stress mode, aggregate interlock plays a limited role in stress transfer, and the mastic phase plays the dominant role through its adhesive/cohesive and viscoelastic properties. Under actual combined loading patterns, any coordinate direction may experience different stress modes; therefore, the mechanical behavior is not the same in the different directions and the asphalt... 

Thermoplastic polyurethane nanocomposites incorporating carbon nanotubes and graphene nanoplatelets were prepared through melt blending and compression molding, and the compounding process was optimized taking into account the different physical properties of one-dimensional carbon nanotubes and two-dimensional graphene nanoplatelets. Filler dispersion was further improved in the case of carbon nanotubes by noncovalent surface modification using a specific surfactant. The well-dispersed nanofillers favored enhanced phase separation in the thermoplastic polyurethane, leading to a better microstructure, which is able to improve the load transfer and maximize the tensile and viscoelastic... 

The stability of a viscoelastic plate strip, subjected to an axial load with the Kelvin–Voigt fractional order constitutive relationship is studied. Based on the classical plate theory, the structural formulation of the plate is obtained by using the Newton’s second law and the aerodynamic force due to the fluid flow is evaluated by piston theory. The Galerkin method is employed to discretize the equation of motion into a set of ordinary differential equations. To determine the stability margin of plate the obtained set of ordinary differential equations are solved using the Laplace transform method. The effects of variation of the governing parameters such as axial force, retardation time,... 

The present experimental study investigated the behavior of hot-mix asphalt (HMA) under repetitive creep and recovery loading. Cylindrical samples of HMA were subjected to trapezoidal and haversine loading followed by unloading. Different amounts of unloading (stress reduction) and relaxation periods (rest periods in complete unloading) were tested. The measured vertical deformation was decomposed into viscoelastic and viscoplastic components. It was observed for cyclic loading that an increase in unloading and/or relaxation period increased the recovery of viscoelastic strain, which in turn increased the accumulated viscoplastic strain in subsequent loading cycles. It appears that... 

In this paper, a constitutive and micromechanical model for prediction of rate-dependent behavior of connective tissues (CTs) is presented. Connective tissues are considered as nonlinear viscoelastic material. The rate-dependent behavior of CTs is incorporated into model using the well-known quasi-linear viscoelasticity (QLV) theory. A planar wavy representative volume element (RVE) is considered based on the tissue microstructure histological evidences. The presented model parameters are identified based on the available experiments in the literature. The presented constitutive model introduced to ABAQUS by means of UMAT subroutine. Results show that, monotonic uniaxial test predictions of...