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Iron-catalyzed inexpensive and practical synthesis of N-substituted pyrroles in water

Azizi, N ; Sharif University of Technology | 2009

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  1. Type of Document: Article
  2. DOI: 10.1055/s-0029-1217799
  3. Publisher: 2009
  4. Abstract:
  5. An operationally simple, practical, and economical protocol for iron(III) chloride catalyzed Paal-Knorr pyrrole synthesis in water in good to excellent yields has been developed. Several N-substituted pyrroles are readily prepared from the reaction of 2,5-dimethoxytetrahydrofuran and aryl/alkyl, sulfonyl and acyl amines under very mild reaction conditions. © Georg Thieme Verlag Stuttgart
  6. Keywords:
  7. Amine ; Dimethoxytetrahydrofuran ; Iron ; Pyrrole ; Water chemistry ; Ferrous ion ; Pyrrole derivative ; Water ; Article ; Catalysis ; chemical analysis ; Chemical reaction ; Chemical structure ; Synthesis ; Temperature measurement
  8. Source: Synlett ; Issue 14 , 2009 , Pages 2245-2248 ; 09365214 (ISSN)
  9. URL: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0029-1217799