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Fully supramolecular vesicles as anticancer drug delivery systems

Pourjavadi, A ; Sharif University of Technology | 2013

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  1. Type of Document: Article
  2. DOI: 10.1039/c2nj40851a
  3. Publisher: 2013
  4. Abstract:
  5. A supramolecular linear-dendritic copolymer consisting of a polystyrene backbone and hanging hyperbranched polyglycerols was prepared and characterized. Host-guest interactions between β-cyclodextrin incorporated in the core of polyglycerol as a host and aromatic rings of polystyrene as guests lead to the formation of a supramolecular linear-dendritic copolymer. Supramolecules formed micelles in aqueous solutions which were able to encapsulate and transfer paclitaxel with a high loading capacity
  6. Keywords:
  7. Beta cyclodextrin ; Copolymer ; Drug carrier ; Glycerol derivative ; Paclitaxel ; Polystyrene ; Aqueous solution ; Drug absorption ; Drug decomposition ; Drug delivery system ; Drug release ; Hydrophobicity ; Particle size ; PH ; Priority journal ; Supramolecular chemistry ; Thermogravimetry
  8. Source: New Journal of Chemistry ; Volume 37, Issue 2 , 2013 , Pages 295-298 ; 11440546 (ISSN)
  9. URL: http://pubs.rsc.org/en/Content/ArticleLanding/2013/NJ/C2NJ40851A#!divAbstract