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Obesity and obesity shape markedly influence spine biomechanics: a subject-specific risk assessment model

Ghezelbash, F ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.1007/s10439-017-1868-7
  3. Abstract:
  4. Underlying mechanisms of obesity-related back pain remain unexplored. Thus, we aim to determine the effect of obesity and its shapes on the spinal loads and the associated risks of injury. Obesity shapes were initially constructed by principal component analysis based on datasets on 5852 obese individuals. Spinal loads, cycles to vertebral failure and trunk stability margin were estimated in a subject-specific trunk model taking account of personalized musculature, passive ligamentous spine, obesity shapes, segmental weights, spine kinematics and bone mineral density. Three obesity shapes (mean and extreme abdominal circumferences) at three body weights (BWs) of 86, 98 and 109 kg were analyzed. Additional BW (12 kg) increased spinal loads by ~11.8%. Higher waist circumferences at identical BW increased spinal forces to the tune of ~20 kg additional BW and the risk of vertebral fatigue compression fracture by 3–7 times when compared with smaller waist circumferences. Forward flexion, greater BW and load in hands increased the trunk stability margin. Spinal loads markedly increased with BW, especially at greater waist circumferences. The risk of vertebral fatigue fracture also substantially increased at greater waist circumferences though not at smaller ones. Obesity and its shape should be considered in spine biomechanics. © 2017, Biomedical Engineering Society
  5. Keywords:
  6. BMD ; Obesity ; Somatotype ; Spinal loads ; Stability ; Trunk musculoskeletal model ; Vertebral fracture ; Convergence of numerical methods ; Fracture ; Loads (forces) ; Musculoskeletal system ; Principal component analysis ; Apple- and pear-shaped ; Musculoskeletal model ; Vertebral fractures ; Nutrition ; Abdominal circumference ; Adult ; Aged ; Biomechanics ; Body fat distribution ; Body weight ; Bone density ; Compression fracture ; Controlled study ; Human ; Kinematics ; Major clinical study ; Priority journal ; Risk assessment ; Risk factor ; Spine fracture ; Waist circumference ; Weight bearing
  7. Source: Annals of Biomedical Engineering ; Volume 45, Issue 10 , 2017 , Pages 2373-2382 ; 00906964 (ISSN)
  8. URL: https://link.springer.com/article/10.1007%2Fs10439-017-1868-7