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Magnetic hyperthermia behaviour of Co and reduced GO nanocomposites

Kakavand, A ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1049/mnl.2019.0272
  3. Publisher: Institution of Engineering and Technology , 2020
  4. Abstract:
  5. Co-precipitation of CoCl2.6H2O with graphene oxide (GO) and heating at 400°C for 4 h under hydrogen resulted in the construction of cobalt/ reduced GO (Co/rGO) nanocomposite utilisable in magnetic thermal therapy. Field emission scanning electron microscopy, transmission electron microscopy, X-ray photoelectron spectroscopy, vibrating sample magnetometry, thermogravimetric analysis/derivative thermogravimetry, and X-ray diffraction methods characterised the samples. Time-temperature curves of the samples containing 30, 50, 70, and 100 µg ml−1 Co/rGO nanoparticles (NPs) suspended in phosphate-buffered saline were determined at different specific heating rates. Magnetic-field response of Co/rGO nanocomposites was better than CoNPs and GO. The biological behaviour of the powders was investigated by 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Co/rGO nanocomposites showed an acceptable biocompatibility behaviour, whereas the CoNPs demonstrated toxic conduct. © The Institution of Engineering and Technology 2020
  6. Keywords:
  7. Biocompatibility ; Chlorine compounds ; Field emission microscopes ; Graphene ; High resolution transmission electron microscopy ; Magnetism ; Magnetometry ; Nanocomposites ; Scanning electron microscopy ; Thermogravimetric analysis ; X ray photoelectron spectroscopy ; Magnetic hyperthermia ; Nanoparticle (NPs) ; Phosphate-buffered salines ; Thermal therapies ; Time-temperature curves ; Vibrating sample magnetometry ; X-ray diffraction method ; Cobalt ; Graphene oxide ; Hydrogen ; Phosphate buffered saline ; Reduced graphene oxide ; Unclassified drug ; Aqueous solution ; Cell proliferation ; Energy dispersive X ray spectroscopy ; Field emission scanning electron microscopy ; Heating ; Magnetic field ; Minimum concentration ; MTT assay ; Precipitation ; Thermogravimetry ; Transmission electron microscopy
  8. Source: Micro and Nano Letters ; Volume 15, Issue 4 , April , 2020 , Pages 239-244
  9. URL: https://ietresearch.onlinelibrary.wiley.com/doi/10.1049/mnl.2019.0272