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A facile and convenient synthesis of 3-alkylidene-oxindoles bearing tetrahydropyrazine scaffold under catalyst-free conditions

Matloubi Moghaddam, F ; Sharif University of Technology | 2018

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  1. Type of Document: Article
  2. DOI: 10.1002/hc.21416
  3. Publisher: Wiley-Blackwell , 2018
  4. Abstract:
  5. A facile and efficient synthesis of 2-oxindole derivatives bearing tetrahydropyrazine scaffold has been developed. Using water as solvent without any additional acid or metal catalyst, easy work up and high yield of products are the main advantages of this protocol. © 2018 Wiley Periodicals, Inc
  6. Keywords:
  7. 2-oxindole ; 3-alkylidene-oxindoles ; Catalyst free ; Pyrazine ; Water
  8. Source: Heteroatom Chemistry ; Volume 29, Issue 2 , March , 2018 ; 10427163 (ISSN)
  9. URL: https://onlinelibrary.wiley.com/doi/full/10.1002/hc.21416