Sharif Digital Repository

In this study, transient diffusion of drug into the intervertebral disc is considered. The amount of Diffused drug from the blood into the intervertebral disc of dog is measured and concentration of drug is calculated for each region of the intervertebral disc including nucleus pulpous, inner annulus fibroses and outer annulus fibroses. Using finite element method, it is shown that the amount of drug diffusion into the intervertebral disc is affected by some parameters such as the type of drug, dose if drug and endplate calcification. This research is done in two parts: In first part, diffusion of drug (sulphate) into the dog intervertebral disc is investigated to compare the obtained... 

The nucleus pulposus, which is a part of intervertebral disc, is normally hydrated and gel-like to maintain normal biomechanical functions of the disc through intradiscal pressures. In a degenerated disc, however, water content of nucleus is significantly reduced, resulting in an abnormal stress state of the annulus. Surgical interventions cannot restore the biomedical function to vertebral segment. One approach to restore the normal biomechanics of an intervertebral disc is to replace the nucleus with a prosthetic material which leads to a restoration of the behavior of the disc. The mechanical behavior of poly(vinyl alcohol) and nanodiamond hydrogel may provide a material suitable for... 

A single-degree-of-freedom model is considered for flexible exercise bars based on the lumped-element approach. By considering the side segment of a flexible exercise bar as a cantilever beam with an equivalent mass at the free end, its free-vibration response and forced one under excitation of the grip of the flexible bar is written parametrically. Some experiments are performed on a specific flexible bar to obtain numerical values for the parameters in the model to have it quantitatively known. In the next step, simulation of the model results in the response of the flexible bar under a considered excitation. The response is imported into a multi-segment musculoskeletal software, AnyBody,... 

Neck fracture caused by impacts on the head and neck during road accidents annually imposes a great cost to the people hospitals and the economy of country. Most of these accidents, regardless of cartilaginous injury causes sudden pressure to the spinal cord so it seems necessary to understand the biomechanical response of the neck and the mechanism of injury to reduce costs. Many computational models related to the neck injury have been developed recently. The aim of this project is to investigate the effect of frontal and rear impacts to the head and neck during road accidents. There are many researches have used elastic property for tissues but a little portion of research in this field... 

Lifting is considered a major risk to people's health in life, particularly to the workers. Appropriate wearable tools for measuring the individual’s kinematic and kinetic movement are required for examining and analyzing the lifting activity to prevent injury in the workplace. Different wearable systems have been developed to calculate the force applied on the foot sole to analyze movement in various areas of gait analysis, occupational biomechanics, sports, and other areas. The accuracy and precision of these systems need to be tested before application in any of these areas. In this study, 3 subjects performed five different activities of symmetrical lifting by placing Pedar insoles in...