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    Global age-sex-specific fertility, mortality, healthy life expectancy (HALE), and population estimates in 204 countries and territories, 1950–2019: a comprehensive demographic analysis for the Global Burden of Disease Study 2019

    , Article The Lancet ; Volume 396, Issue 10258 , 2020 , Pages 1160-1203 Abbafati, C ; Machado, D.B ; Cislaghi, B ; Salman, O.M ; Karanikolos, M ; McKee, M ; Abbas, K.M ; Brady, O.J ; Larson, H.J ; Trias-Llimós, S ; Cummins, S ; Langan, S.M ; Sartorius, B ; Hafiz, A ; Jenabi, E ; Mohammad Gholi Mezerji, N ; Borzouei, S ; Azarian, G ; Khazaei, S ; Abbasi, M ; Asghari, B ; Masoumi, S ; Komaki, H ; Taherkhani, A ; Adabi, M ; Abbasifard, M ; Bazmandegan, G ; Kamiab, Z ; Vakilian, A ; Anjomshoa, M ; Mokari, A ; Sabour, S ; Shahbaz, M ; Saeedi, R ; Ahmadieh, H ; Yousefinezhadi, T ; Haj-Mirzaian, A ; Nikbakhsh, R ; Safi, S ; Asgari, S ; Irvani, S.N ; Jahanmehr, N ; Ramezanzadeh, K ; Abbasi-Kangevari, M ; Khayamzadeh, M ; Abbastabar, H ; Shirkoohi, R ; Fazlzadeh, M ; Janjani, H ; Hosseini, M ; Mansournia, M ; Tohidinik, H ; Bakhtiari, A ; Fazaeli, A ; Mousavi, S ; Hasanzadeh, A ; Nabavizadeh, B ; Malekzadeh, R ; Hashemian, M ; Pourshams, A ; Salimzadeh, H ; Sepanlou, S.G ; Afarideh, M ; Esteghamati, A ; Esteghamati, S ; Ghajar, A ; Heidari, B ; Rezaei, N ; Mohamadi, E ; Rahimi-Movaghar, A ; Rahim, F ; Eskandarieh, S ; Sahraian, M ; Mohebi, F ; Aminorroaya, A ; Ebrahimi, H ; Farzadfar, F ; Mohajer, B ; Pishgar, F ; Saeedi Moghaddam, S ; Shabani, M ; Zarafshan, H ; Abolhassani, H ; Hafezi-Nejad, N ; Heidari-Soureshjani, R ; Abdollahi, M ; Farahmand, M ; Salamati, P ; Mehrabi Nasab, E ; Tajdini, M ; Aghamir, S ; Mirzaei, R ; Dibaji Forooshani, Z ; Khater, M.M ; Abd-Allah, F ; Abdelalim, A ; Abualhasan, A ; El-Jaafary, S.I ; Hassan, A ; Elsharkawy, A ; Khater, A.M ; Elhabashy, H.R ; Salem, M.R.R ; Salem, H ; Sadeghi, M ; Jafarinia, M ; Amini-Rarani, M ; Mohammadifard, N ; Sarrafzadegan, N ; Abdollahpour, I ; Sarveazad, A ; Tehrani-Banihashemi, A ; Yoosefi Lebni, J ; Manafi, N ; Pazoki Toroudi, H ; Dorostkar, F ; Alipour, V ; Sheikhtaheri, A ; Arabloo, J ; Azari, S ; Ghashghaee, A ; Rezapour, A ; Naserbakht, M ; Kabir, A ; Mehri, F ; Yousefifard, M ; Asadi-Aliabadi, M ; Babaee, E ; Eshrati, B ; Goharinezhad, S ; Moradi-Lakeh, M ; Abedi, P ; Rashedi, V ; Kumar, V ; Elgendy, I.Y ; Basu, S ; Park, J ; Pereira, A ; Norheim, O.F ; Eagan, A.W ; Cahill, L.E ; Sheikh, A ; Abushouk, A.I ; Kraemer, M.U.G ; Thakur, B ; Bärnighausen, T.W ; Shrime, M.G ; Abedi, A ; Doshi, C.P ; Abegaz, K.H ; Geberemariyam, B.S ; Aynalem, Y.A ; Shiferaw, W.S ; Abosetugn, A.E ; Aboyans, V ; Abrams, E.M ; Gitimoghaddam, M ; Kissoon, N ; Stubbs, J.L ; Brauer, M ; Iyamu, I.O ; Kopec, J.A ; Pourmalek, F ; Ribeiro, A.P ; Malta, D.C ; Gomez, R.S ; Abreu, L.G ; Abrigo, M.R.M ; Almulhim, A.M ; Dahlawi, S.M.A ; Pottoo, F.H ; Menezes, R.G ; Alanzi, T.M ; Alumran, A.K ; Abu Haimed, A.K ; Madadin, M ; Alanezi, F.M ; Abu-Gharbieh, E ; Saddik, B ; Abu-Raddad, L.J ; Samy, A.M ; El Nahas, N ; Shalash, A.S ; Nabhan, A.F ; Kamath, A.M ; Kassebaum, N.J ; Aravkin, A.Y ; Kochhar, S ; Sorensen, R.J.D ; Afshin, A ; Burkart, K ; Cromwell, E.A ; Dandona, L ; Dharmaratne, S.D ; Gakidou, E ; Hay, S.I ; Kyu, H.H ; Lopez, A.D ; Lozano, R ; Misganaw, A.T ; Mokdad, A.H ; Naghavi, M ; Pigott, D.M ; Reiner Jr, R.C ; Roth, G.A ; Stanaway, J.D ; Vollset, S ; Vos, T ; Wang, H ; Lim, S.S ; Murray, C.J.L ; Kalani, R ; Ikuta, K.S ; Cho, D.Y ; Kneib, C.J ; Crowe, C.S ; Massenburg, B.B ; Morrison, S.D ; Acebedo, A ; Adelson, J.D ; Agesa, K.M ; Alam, T ; Albertson, S.B ; Anderson, J.A ; Antony, C.M ; Ashbaugh, C ; Assmus, M ; Azhar, G ; Balassyano, S ; Bannick, M.S ; Barthelemy, C.M ; Bender, R.G ; Bennitt, F.B ; Bertolacci, G.J ; Biehl, M.H ; Bisignano, C ; Boon-Dooley, A.S ; Briant, P.S ; Bryazka, D ; Bumgarner, B.R ; Callender, C.S ; Cao, J ; Castle, C.D ; Castro, E ; Causey, K ; Cercy, K.M ; Chalek, J ; Charlson, F.J ; Cohen, A.J ; Comfort, H ; Compton, K ; Croneberger, A.J ; Cruz, J.A ; Cunningham, M ; Dandona, R ; Dangel, W.J ; Dean, F.E ; DeCleene, N.K ; Deen, A ; Degenhardt, L ; Dingels, Z.V ; Dippenaar, I.N ; Dirac, M.A ; Dolgert, A.J ; Emmons-Bell, S ; Estep, K ; Farag, T ; Feigin, V.L ; Feldman, R ; Ferrara, G ; Ferrari, A.J ; Fitzgerald, R ; Force, L.M ; Fox, J.T ; Frank, T.D ; Fu, W ; Fukutaki, K ; Fuller, J.E ; Fullman, N ; Galles, N.C ; Gardner, W.M ; Gershberg Hayoon, A ; Goren, E ; Gorman, T.M ; Gottlich, H.C ; Guo, G ; Haddock, B ; Hagins, H ; Haile, L.M ; Hamilton, E.B ; Han, C ; Han, H ; Harvey, J.D ; Henny, K ; Henrikson, H.J ; Henry, N.J ; Herbert, M.E ; Hsiao, T ; Huynh, C.K ; Iannucci, V.C ; Ippolito, H ; Irvine, C.M.S ; Jafari, H ; Jahagirdar, D ; James, S.L ; Johnson, C.O ; Johnson, S.C ; Keller, C ; Kemmer, L ; Kendrick, P.J ; Knight, M ; Kocarnik, J.M ; Krohn, K.J ; Larson, S.L ; Lau, K.M ; Ledesma, J.R ; Leever, A.T ; LeGrand, K.E ; Lescinsky, H ; Lin, C ; Liu, H ; Liu, Z ; Lo, J ; Lu, A ; Ma, J ; Maddison, E.R ; Manguerra, H ; Marks, A ; Martopullo, I ; Mastrogiacomo, C.I ; May, E.A ; Mooney, M.D ; Mosser, J.F ; Mullany, E.C ; Mumford, J ; Munro, S.B ; Nandakumar, V ; Nguyen, J ; Nguyen, M ; Nichols, E ; Nixon, M.R ; Odell, C.M ; Ong, K.L ; Orji, A.U ; Ostroff, S.M ; Pasovic, M ; Paulson, K.R ; Pease, S.A ; Pennini, A ; Pierce, M ; Pilz, T.M ; Pletcher, M ; Rao, P.C ; Razo, C ; Redford, S.B ; Reinig, N ; Reitsma, M.B ; Rhinehart, P ; Robalik, T ; Roberts, S ; Roberts, N.L.S ; Rolfe, S ; Sbarra, A.N ; Schaeffer, L.E ; Shackelford, K.A ; Shadid, J ; Sharara, F ; Shaw, D.H ; Sheena, B.S ; Simpson, K.E ; Smith, A ; Spencer, C.N ; Spurlock, E.E ; Stark, B.A ; Steiner, C ; Steuben, K.M ; Sylte, D.O ; Tang, M ; Taylor, H.J ; Terrason, S ; Thomson, A.M ; Torre, A.E ; Travillian, R ; Troeger, C.E ; Vongpradith, A ; Walters, M.K ; Wang, J ; Watson, A ; Watson, S ; Whisnant, J.L ; Whiteford, H.A ; Wiens, K.E ; Wilner, L.B ; Wilson, S ; Wool, E.E ; Wozniak, S.S ; Wu, J ; Wulf Hanson, S ; Wunrow, H ; Xu, R ; Sharif University of Technology
    Lancet Publishing Group  2020
    Abstract
    Background: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected subnational locations from 1950 to 2019. Methods: 8078 country-years of vital registration and sample registration data, 938 surveys, 349 censuses, and 238 other sources were identified and used to estimate age-specific fertility. Spatiotemporal... 

    Fabrication of carboxymethyl chitosan/poly(ε-caprolactone)/doxorubicin/nickel ferrite core-shell fibers for controlled release of doxorubicin against breast cancer

    , Article Carbohydrate Polymers ; Volume 257 , 2021 ; 01448617 (ISSN) Abasalta, M ; Asefnejad, A ; Khorasani, M. T ; Saadatabadi, A. R ; Sharif University of Technology
    Elsevier Ltd  2021
    Abstract
    The coaxial electrospinning for producing core-shell nanofibers due to control the release profile of drug by the shell layer has been developed. N-carboxymethyl chitosan (CMC)-polyvinyl alcohol (core)/poly(ε-caprolactone) (PCL) (shell) nanofibers were produced via coaxial electrospinning. Doxorubicin (DOX) and nickel ferrite nanoparticles were incorporated into the nanofibers for controlled release of DOX against MCF-7 breast cancer. The minimum CMC/PCL fiber diameter was found to be 300 nm by optimizing of three variables including voltage to distance ratio (1.5–2.5 kV/cm), CMC concentration (4−6 wt.%) and PCL concentration (8−12 wt.%). The synthesized core-shell fibers were characterized... 

    Fabrication of carboxymethyl chitosan/poly(ε-caprolactone)/doxorubicin/nickel ferrite core-shell fibers for controlled release of doxorubicin against breast cancer

    , Article Carbohydrate Polymers ; Volume 257 , 2021 ; 01448617 (ISSN) Abasalta, M ; Asefnejad, A ; Khorasani, M. T ; Saadatabadi, A. R ; Sharif University of Technology
    Elsevier Ltd  2021
    Abstract
    The coaxial electrospinning for producing core-shell nanofibers due to control the release profile of drug by the shell layer has been developed. N-carboxymethyl chitosan (CMC)-polyvinyl alcohol (core)/poly(ε-caprolactone) (PCL) (shell) nanofibers were produced via coaxial electrospinning. Doxorubicin (DOX) and nickel ferrite nanoparticles were incorporated into the nanofibers for controlled release of DOX against MCF-7 breast cancer. The minimum CMC/PCL fiber diameter was found to be 300 nm by optimizing of three variables including voltage to distance ratio (1.5–2.5 kV/cm), CMC concentration (4−6 wt.%) and PCL concentration (8−12 wt.%). The synthesized core-shell fibers were characterized...