Dynamics of Magnetic Nanoparticles in Biologically Inspired Flows under Effect of Electric and Magnetic Fields with Application in Epilepsy Detection

Please enable javascript in your browser.

Zamani Pedram, Maysam | 2016

878 Viewed

Type of Document: Ph.D. Dissertation
Language: Farsi
Document No: 49007 (08)
University: Sharif University of Technology
Department: Mechanical Engineering
Advisor(s): Alasty, Aria; Ghaffarzadeh, Ebrahim; Shamloo, Amir
Abstract:
This thesis presents my Ph.D. research study focusing on the dynamic analysis of magnetic nanoparticles (MNPs) for epilepsy and blood-brain barrier (BBB) applications. In this analysis, we took into account various parameters including the magnetic field, fluid behavior, geometry and material of MNPs. Based on this computational study, the generated magnetic field in epileptic foci results in the aggregation of nanoparticles. This may offer the advantage of using MNPs as a Magnetic Resonance Imaging (MRI) contrast agent. Furthermore, in this study, we also demonstrated and discussed the advantage of MNPs for crossing BBB using the external magnetic field. The outcome of this research project opens a new avenue in the field of bioengineering for using MNPs as an emerging tool for detecting brain diseases including epilepsy
Keywords:
Magnetic Nanodot ; Epileptic Seizure Detection ; Magnetic Fields ; Nanosensor ; Epilepsy ; Nano-biosensor ; Biomedical Microelectromechanical System (Bio-MEMS) ; Blood Brain Barrier

No TOC