Loading...

Simultaneous electrodeposition of reduced graphene oxide/ag nanoparticles as a sensitive layer for voltammetric determination of tinidazole

Shahrokhian, S ; Sharif University of Technology | 2017

629 Viewed
  1. Type of Document: Article
  2. DOI: 10.1142/S1793292017500679
  3. Publisher: World Scientific Publishing Co. Pte Ltd , 2017
  4. Abstract:
  5. A stable composite film of silver nanoparticles (Ag NPs) decorated on reduced graphene oxide is prepared by a two-step simple procedure. The surface morphology of the modified electrode is characterized by scanning electron microscopy (SEM) and atomic force microscopy (AFM) techniques. The electrochemical behavior of tinidazole (TNZ) on the surface of the modified electrode is investigated by linear sweep voltammetry and electrochemical impedance spectroscopy. The prepared composite electrode acts as a highly sensitive platform for the voltammetric determination of TNZ, leading to a significant increase in the reduction peak current of TNZ. The effects of experimental parameters such as the amount of the casted silver ions-GO mixture suspension, the electro-reduction variables, the accumulation time and potential, the scan rate and pH of the buffered solutions on the electrochemical response of TNZ are investigated. Under optimal conditions, the modified electrode showed a wide linear range for the reduction of TNZ in the range of 0.01-10μM with a detection limit of 3nM. Finally, the prepared electrode is successfully applied for the determination of TNZ in pharmaceutical and clinical samples. © 2017 World Scientific Publishing Company
  6. Keywords:
  7. Composite modified electrode ; Electrochemical reduction ; Reduced grahene oxide ; Tinidazole ; Atomic force microscopy ; Chemical sensors ; Composite films ; Electrochemical impedance spectroscopy ; Electrodes ; Electrolytic reduction ; Graphene ; Metal ions ; Metal nanoparticles ; Nanocomposite films ; Nanoparticles ; Reduction ; Scanning electron microscopy ; Silver ; Voltammetry ; Composite modified electrodes ; Electrochemical reductions ; Reduced graphene oxides ; Silver nanoparticles ; Electrochemical electrodes
  8. Source: Nano ; Volume 12, Issue 6 , 2017 ; 17932920 (ISSN)
  9. URL: https://www.worldscientific.com/doi/abs/10.1142/S1793292017500679