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In vitro dissolution of plasma-sprayed hydroxyapatite coatings with different characteristics: Experimental study and modeling

Mohammadi, Z ; Sharif University of Technology | 2008

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  1. Type of Document: Article
  2. DOI: 10.1088/1748-6041/3/1/015006
  3. Publisher: 2008
  4. Abstract:
  5. The dissolution of plasma-sprayed hydroxyapatite (PHA) coatings with different characteristics, produced by various spraying conditions, in a Tris-buffered solution at pH 7.4 was experimentally studied through the measurement of the release of calcium ions. The phase composition of the coatings at surface and interface, and the porosity were evaluated. The analytical modeling revealed that the calcium dissolution process was composed of two stages. The first stage was found to be both surface and diffusion controlled. The second stage was an exactly diffusion-controlled dissolution. In the first stage, the rate of dissolution and the solubility of the coatings with minimum contents of impurity phases were mainly influenced by the contents of recrystallized HA (RHA) and amorphous calcium phosphate (ACP). It is suggested that the optimized values of the ACP and the RHA at the coating surface can tend to encourage the early fixation properties of the PHA coatings. © 2008 IOP Publishing Ltd
  6. Keywords:
  7. Amorphous calcium phosphate ; Calcium ion ; Calcium phosphate ; Hydroxyapatite ; Trometamol ; Unclassified drug ; Biomaterial ; Akalinity ; Calcium transport ; Diffusion ; Dissolution ; Material coating ; Model ; Plasma ; Porosity ; Reaction time ; Body fluid ; Chemical model ; Chemistry ; Colloid ; Comparative study ; Computer simulation ; Evaluation ; Gas ; Materials testing ; Methodology ; Body Fluids ; Coated Materials, Biocompatible ; Colloids ; Durapatite ; Gases ; Heat ; Models, Chemical ; Crystallization
  8. Source: Biomedical Materials ; Volume 3, Issue 1 , 2008 ; 17486041 (ISSN)
  9. URL: https://iopscience.iop.org/article/10.1088/1748-6041/3/1/015006