Loading...
Synthesis, characterisation and crystal structure of a new Cu(II)-carboxamide complex and CuO nanoparticles as new catalysts in the CuAAC reaction and investigation of their antibacterial activity
565 viewed

Synthesis, characterisation and crystal structure of a new Cu(II)-carboxamide complex and CuO nanoparticles as new catalysts in the CuAAC reaction and investigation of their antibacterial activity

Kiani, M

Synthesis, characterisation and crystal structure of a new Cu(II)-carboxamide complex and CuO nanoparticles as new catalysts in the CuAAC reaction and investigation of their antibacterial activity

Kiani, M ; Sharif University of Technology | 2020

565 Viewed
  1. Type of Document: Article
  2. DOI: 10.1016/j.ica.2020.119514
  3. Publisher: Elsevier S. A , 2020
  4. Abstract:
  5. The bidentate carboxamide ligand N-(thiazole-2-yl) picolinamide (LH) was synthesized in the environmentally friendly ionic liquid TBAB, and the five-coordinated CuII-complex, [Cu(L)2(H2O)].CHCl3 (1) was synthesized from LH and copper(II)acetate. Cupric oxide [CuO] nanoparticles (2) have been prepared by the thermal decomposition of (1) as a new precursor at 600 °C for 3 h under air atmosphere. (1) was characterised using FT-IR spectroscopy, elemental analyses and its solid state structure was confirmed by single crystal X-ray diffraction. (2) were identified by FT-IR spectroscopy, X-ray powder diffraction, scanning electron microscopy, energy dispersive X-ray analysis and thermo-gravimetric differential thermal analyses. The electrochemical behaviour of LH and (1) has been investigated by cyclic voltammetry: irreversible CuII/I reductions were observed. The catalytic activity of (1) and (2) were evaluated in the one-pot azide–alkyne cycloaddition click reaction in water without additional agents. LH, (1) and (2) were also screened for their in vitro antibacterial activity: they showed promising antibacterial activity comparable to that of the antibiotic penicillin. © 2020 Elsevier B.V
  6. Keywords:
  7. Azide–alkyne cycloaddition and antibacterial activity ; Cu(II)-carboxamide complex ; N-(thiazole-2-yl) picolinamide ; Catalyst activity ; Coordination reactions ; Crystal structure ; Cyclic voltammetry ; Decomposition ; Differential thermal analysis ; Energy dispersive X ray analysis ; Hydrocarbons ; Ionic liquids ; Nanocatalysts ; Nanoparticles ; Scanning electron microscopy ; Single crystals ; Spacecraft instruments ; Synthesis (chemical) ; X ray powder diffraction ; Anti-bacterial activity ; Carboxamides ; CuO nanoparticles ; Electrochemical behaviour ; FTIR spectroscopy ; Single crystal x-ray diffraction ; Solid-state structures ; Thermo-gravimetric ; Copper oxides
  8. Source: Inorganica Chimica Acta ; Volume 506 , June , 2020
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S0020169319318432