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Effect of synthesis temperature of magnetic–fluorescent nanoparticles on properties and cellular imaging

Sahebalzamani, H ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1007/s10904-020-01720-5
  3. Publisher: Springer , 2020
  4. Abstract:
  5. The excellent photoluminescent properties of Fe3O4-graphene quantum dots (Fe3O4/GQD) nanoparticles prepared at 30 and 90 °C have made them as promising optical probes for imaging. Herein, the cytotoxicity of GQD and Fe3O4/GQD nanoparticles in L929 cells was investigated using MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium Bromide] assay. The cellular apoptosis or necrosis was then evaluated by flow cytometry analysis. The Fe3O4/GQD nanoparticles were characterized by transmission electron microscopy (TEM), Raman spectroscopy (Raman), Fourier-transform infrared spectroscopy (FT-IR), photoluminescence (PL). Characterization results obtained, clearly show that Fe3O4/GQD nanoparticles at 30 and 90 °C has been successfully prepared. Water solubility and excellent photostability along with low cytotoxicity of Fe3O4/GQD nanoparticles prepared at 30 and 90 °C were manifested as a remarkable bioimaging material. © 2020, Springer Science+Business Media, LLC, part of Springer Nature
  6. Keywords:
  7. Apoptosis ; Fe3O4/GQD ; Fluorescence imaging ; MTT ; Necrosis ; Cell death ; Fourier transform infrared spectroscopy ; Graphene quantum dots ; High resolution transmission electron microscopy ; Iron oxides ; Magnetite ; Nanoparticles ; Semiconductor quantum dots ; Synthesis (chemical) ; Cellular imaging ; Flow cytometry analysis ; Fluorescent nanoparticles ; Fourier transform infra red (FTIR) spectroscopy ; Low cytotoxicities ; Photo-luminescent properties ; Synthesis temperatures ; Water solubilities ; Nanomagnetics
  8. Source: Journal of Inorganic and Organometallic Polymers and Materials ; Volume 30, Issue 11 , 2020 , Pages 4597-4605
  9. URL: https://link.springer.com/article/10.1007/s10904-020-01720-5