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Engineered Biomimetic Membranes for Organ-on-a-Chip

Rahimnejad, M ; Sharif University of Technology | 2022

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  1. Type of Document: Article
  2. DOI: 10.1021/acsbiomaterials.2c00531
  3. Publisher: American Chemical Society , 2022
  4. Abstract:
  5. Organ-on-a-chip (OOC) systems are engineered nanobiosystems to mimic the physiochemical environment of a specific organ in the body. Among various components of OOC systems, biomimetic membranes have been regarded as one of the most important key components to develop controllable biomimetic bioanalysis systems. Here, we review the preparation and characterization of biomimetic membranes in comparison with the features of the extracellular matrix. After that, we review and discuss the latest applications of engineered biomimetic membranes to fabricate various organs on a chip, such as liver, kidney, intestine, lung, skin, heart, vasculature and blood vessels, brain, and multiorgans with perspectives for further biomedical applications. © 2022 American Chemical Society. All rights reserved
  6. Keywords:
  7. Artificial organ ; Bioanalysis ; Biomembrane ; Organ-on-a-chip ; Tissue engineering ; Artificial organs ; Biomimetics ; Blood vessels ; Medical applications ; Biomembranes ; Biomimetic membrane ; Chip system ; Extracellular matrices ; Nanobiosystems ; Organ-on-a-chip ; Physiochemical environments ; Tissues engineerings ; Vasculature ; Lab on a chip ; Membrane ; Tissue engineering ; Lab-On-A-Chip Devices ; Membranes ; Microphysiological Systems
  8. Source: ACS Biomaterials Science and Engineering ; Volume 8, Issue 12 , 2022 , Pages 5038-5059 ; 23739878 (ISSN)
  9. URL: https://pubs.acs.org/doi/10.1021/acsbiomaterials.2c00531