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Graphene: Promises, facts, opportunities, and challenges in nanomedicine

Mao, H. Y ; Sharif University of Technology | 2013

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  1. Type of Document: Article
  2. DOI: 10.1021/cr300335p
  3. Publisher: 2013
  4. Abstract:
  5. Graphene, a two-dimensional (2D) sheet of sp2-hybridized carbon atoms packed into a honeycomb lattice, has led to an explosion of interest in the field of materials science, physics, chemistry, and biotechnology since the few-layers graphene (FLG) flakes were isolated from graphite in 2004. For an extended search, derivatives of nanomedicine such as biosensing, biomedical, antibacterial, diagnosis, cancer and photothermal therapy, drug delivery, stem cell, tissue engineering, imaging, protein interaction, DNA, RNA, toxicity, and so on were also added. Since carbon nanotubes are normally described as rolled-up cylinders of graphene sheets and the controllable synthesis of nanotubes is well developed, longitudinally unzipping carbon nanotubes represents a novel strategy to obtain graphene nanoribbons (GNRs) of precise dimensions
  6. Keywords:
  7. Carbon atoms ; Controllable synthesis ; Graphene nanoribbons (GNRs) ; Graphene sheets ; Honeycomb lattices ; Novel strategies ; Photothermal therapy ; Protein interaction ; Carbon nanotubes ; Drug delivery ; Graphene ; Medical nanotechnology ; RNA ; Stem cells ; Tissue engineering ; Two dimensional ; Nanoribbons ; Diagnostic agent ; Graphite ; Protein ; Animal ; Chemistry ; Drug delivery system ; Genetic procedures ; Human ; Metabolism ; Methodology ; Review ; Animals ; Biosensing Techniques ; Drug Delivery Systems ; Humans ; Nanomedicine ; Phototherapy ; Proteins
  8. Source: Chemical Reviews ; Volume 113, Issue 5 , 2013 , Pages 3407-3424 ; 00092665 (ISSN)
  9. URL: http://pubs.acs.org/doi/abs/10.1021/cr300335p