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Metabolomics fingerprinting of the human seminal plasma of asthenozoospermic patients

Gilany, K ; Sharif University of Technology

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  1. Type of Document: Article
  2. DOI: 10.1002/mrd.22284
  3. Abstract:
  4. It is estimated that 20% of couples are infertile, and half of these infertility cases are linked to men. One of conditions that can affect male fertility is asthenozoospermia. We applied Raman spectroscopy to the analysis of the metabolome of the human seminal plasma, and used chemometrics on the patterns of Raman spectra obtained. Significant changes were observed in the metabolome of the human seminal plasma of asthenozoospermic patients
  5. Keywords:
  6. Asthenospermia ; Blood sampling ; Chemometrics ; Clinical article ; Human cell ; Infertility therapy ; Molecular dynamics ; Molecular weight ; priority journal ; Raman spectrometry ; Seminal plasma ; Spermatozoon count ; Spermatozoon motility ; Asthenozoospermia ; Humans ; Male ; Metabolome ; Metabolomics ; Semen ; Spectrum Analysis, Raman
  7. Source: Molecular Reproduction and Development ; Vol. 81, Issue. 1 , 2014 , pp. 84-86 ; ISSN: 1098-2795
  8. URL: http://onlinelibrary.wiley.com./doi/10.1002/mrd.22284/abstract;jsessionid=404F74E1456BAFC5A9EFAFA2E6CA9E7C.f01t04