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Silver nanoparticles with gelatin nanoshells: Photochemical facile green synthesis and their antimicrobial activity

Pourjavadi, A ; Sharif University of Technology | 2011

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  1. Type of Document: Article
  2. DOI: 10.1007/s11051-011-0428-6
  3. Publisher: 2011
  4. Abstract:
  5. In the current study, a facile green synthesis of silver-gelatin core-shell nanostructures (spherical, spherical/cubic hybrid, and cubic, DLS diameter: 4.1-6.9 nm) is reported via the wet chemical synthesis procedure. Sunlight-UV as an available reducing agent cause mild reduction of silver ions into the silver nanoparticles (Ag-NPs). Gelatin protein, as an effective capping/shaping agent, was used in the reaction to self-assemble silver nanostructures. The formation of silver nanostructures and their self-assembly pattern was confirmed by SEM, AFM, and TEM techniques. Further investigations were carried out using zeta-potential, UV-Vis, FTIR, GPC, and TGA/DTG/DTA data. The prepared Ag-NPs showed proper and acceptable antimicrobial activity against three classes of microorganisms (Escherichia coli Gram-negative bacteria, Staphylococcus aureus Gram-positive bacteria, and Candida albicans fungus). The antibacterial and antifungal Ag-NPs exhibit good stability in solution and can be considered as promising candidates for a wide range of biomedical applications
  6. Keywords:
  7. Green synthesis ; AFM ; Anti-fungal ; Anti-microbial activity ; Biomedical applications ; Candida albicans ; Core-shell nanostructures ; FTIR ; Good stability ; Gram-negative bacteria ; Gram-positive bacterium ; Nanoshells ; Self-assemble ; Self-assembly patterns ; Silver ions ; Wet chemical synthesis ; Bacteria ; Bacteriology ; Escherichia coli ; Medical applications ; Metal ions ; Nanoparticles ; Nanostructured materials ; Synthesis (chemical) ; Silver ; Gelatin ; Silver nanoparticle ; Antifungal activity ; Drug stability ; Drug synthesis ; Green chemistry ; Nonhuman ; Photochemistry ; Priority journal ; Reaction analysis ; Reduction ; Staphylococcus aureus ; Ultraviolet radiation
  8. Source: Journal of Nanoparticle Research ; Volume 13, Issue 10 , October , 2011 , Pages 4647-4658 ; 13880764 (ISSN)
  9. URL: http://link.springer.com/article/10.1007%2Fs11051-011-0428-6