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Developmental barcoding of whole mouse via homing CRISPR

Kalhor, R ; Sharif University of Technology

1245 Viewed

Type of Document: Article
DOI: 10.1126/science.aat9804
Keywords:
Guide RNA ; Bioengineering ; Cell component ; Developmental biology ; Genome ; Mutation ; Protein ; RNA ; Rodent ; Vertebrate ; Adult ; Allele ; Animal experiment ; Animal tissue ; Brain development ; Clustered regularly interspaced short palindromic repeat ; Controlled study ; DNA barcoding ; Embryo ; Female ; Gene mutation ; Genetic variability ; Male ; Mouse ; Mutagenesis ; Mutant ; Nonhuman ; Pregnancy ; Priority journal
Source: Science ; Volume 361, Issue 6405 , 2018 ; 00368075 (ISSN)
URL: http://science.sciencemag.org/content/361/6405/eaat9804