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High-gravity-assisted green synthesis of palladium nanoparticles: the flowering of nanomedicine

Kiani, M ; Sharif University of Technology | 2020

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  1. Type of Document: Article
  2. DOI: 10.1016/j.nano.2020.102297
  3. Publisher: Elsevier Inc , 2020
  4. Abstract:
  5. This study investigated the synthesis of Pd nanoparticles (NPs) using a high-gravity technique mediated by Salvia hispanica leaf extracts. Biological assays confirmed their antibacterial activity against gram positive (S. aureus) and gram negative (E. coli) bacteria with significant antioxidant activity in comparison with the standards as well as low cellular toxicity on PC12 and HEK293 cell lines. To the best of our knowledge, this study can be considered as the first investigation of Pd-NPs synthesized by Salvia hispanica leaf extracts assisted by a high-gravity technique. In addition, the mentioned green synthesis procedure led to the formation of nanoparticles with considerable antibacterial properties independent of the morphology and texture of the green media of these nanoparticles. Considering the increasing rate of antimicrobial resistant bacteria deaths worldwide, this study introduces a novel green synthesis method and non-antibiotic nanoparticle which should be studied for a wide range of medical applications. © 2020 Elsevier Inc
  6. Keywords:
  7. Green synthesis ; Nanomedicine ; Palladium nanoparticles ; Salvia hispanica ; Bacteria ; Cell culture ; Medical applications ; Medical nanotechnology ; Nanoparticles ; Palladium ; Textures ; Antibacterial properties ; Biological assays ; Cellular toxicities ; Resistant bacteria ; Synthesis procedure ; Butylcresol ; Gentamicin ; Penicillin derivative ; Plant extract ; Antioxidant activity ; Chia ; DPPH radical scavenging assay ; Drug cytotoxicity ; Drug structure ; Drug synthesis ; Escherichia coli ; Field emission scanning electron microscopy ; Fourier transform infrared spectroscopy ; Gravity ; Green chemistry ; HEK293 cell line ; Human cell ; Nanocatalysis ; Nonhuman ; PC12 cell line (pheochromocytoma) ; Photon correlation spectroscopy ; Plant leaf ; Staphylococcus aureus ; X ray diffraction ; Zone of inhibition
  8. Source: Nanomedicine: Nanotechnology, Biology, and Medicine ; Volume 30 , November , 2020
  9. URL: https://www.sciencedirect.com/science/article/abs/pii/S1549963420301519