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Microfluidic devices with gold thin film channels for chemical and biomedical applications: a review

Ghasemi Toudeshkchoui, M ; Sharif University of Technology | 2019

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  1. Type of Document: Article
  2. DOI: 10.1007/s10544-019-0439-0
  3. Publisher: Springer New York LLC , 2019
  4. Abstract:
  5. Microfluidic systems (MFS) provide a range of advantages in biomedical applications, including improved controllability of material characteristics and lower consumption of reagents, energy, time and money. Fabrication of MFS employs various materials, such as glass, silicon, ceramics, paper, and metals such as gold, copper, aluminum, chromium and titanium. In this review, gold thin film microfluidic channels (GTFMFC) are discussed with reference to fabrication methods and their diverse use in chemical and biomedical applications. The advantages of gold thin films (GTF) include flexibility, ease of manufacture, adhesion to polymer surfaces, chemical stability, good electrical conductivity, surface plasmon resonance effects, ability to be chemically functionalized, etc. Various electroactuators and electroanalytical devices can incorporate GTF. GTF-based MFS have been used in environmental monitoring, assays of biomarkers, immunoassays, cell culture studies and pathogen identification. © 2019, Springer Science+Business Media, LLC, part of Springer Nature
  6. Keywords:
  7. Biomedical applications ; Gold thin film channels ; Microfluidic systems ; Surface plasmonic resonance ; Cell culture ; Chemical stability ; Electrochemical sensors ; Fluidic devices ; Gold ; Medical applications ; Microfluidics ; Plasmonics ; Polymer films ; Thin film circuits ; Electrical conductivity ; Environmental Monitoring ; Gold thin films ; Material characteristics ; Micro fluidic system ; Surface plasmon resonance effects ; Surface plasmonic resonances ; Thin films ; biological marker ; Article ; Biomedicine ; Chemical bond ; Chemical modification ; Chemical procedures ; Chemistry ; Drug delivery system ; Electric conductivity ; Electrochemical detection ; Electrochemistry ; Human ; Immunoassay ; Microencapsulation ; Nonhuman ; Priority journal ; Surface plasmon resonance ; Tissue engineering ; Wet chemical etching ; Devices ; Lab on a chip ; Medical research ; Biomedical Research ; Lab-On-A-Chip Devices
  8. Source: Biomedical Microdevices ; Volume 21, Issue 4 , 2019 ; 13872176 (ISSN)
  9. URL: https://link.springer.com/article/10.1007/s10544-019-0439-0